| .smp |
SmilePlant Project Data File |
| .sngx |
ChordWizard Song |
| .sng |
Korg Trinity Song File |
| .s3m |
ScreamTracker 3 Module |
| .smf |
StarMath Formula File |
| .sd2 |
Sound Designer II File |
| .swa |
Shockwave Audio |
| .sprg |
Synclavier Program File |
| .sf2 |
SoundFont 2 Sound Bank |
| .syx |
MIDI System Exclusive Message |
| .sd |
ESPS Sampled Data File |
| .sc2 |
SimCity 2000 City File |
| .sou |
SBStudio II Sound File |
| .s3i |
Scream Tracker 3 Instrument |
| .sbk |
sound font files |
| .sbi |
Sound Blaster Instrument |
| .sds |
MIDI Sample Dump Standard File |
| .sppack |
SPPack Sound Sample |
| .syh |
Synchomatic Instrument |
| .syw |
Yamaha SY99/SY85 Audio File |
| .sfk |
Sound Forge Pro Audio Peak File |
| .shn |
Shorten Compressed Audio File |
| .sfl |
Sound Forge Pro Sound Data File |
| .sfs |
Kerbal Space Program Save File |